Wednesday, 6 August 2008

Interferon Or Surgery For Eye Surface Cancer - Which Is Best?

�James Chodosh, MD, and colleagues evaluated 29 patients who were treated within a 10-year period for ocular surface squamous neoplasia (OSSN), a type of cancer, either by surgical removal of the tumor or with topical interferon (alfa-2b). There were no statistically important differences in age, gender-affected eye and tumor size between patients in the two groups. Risk factors for this form of cancer include advanced eld, light peel, extensive UV-light exposure, smoke, and exposure on the job to petroleum products. HPV (human papilloma virus) and HIV have too been associated with higher rates of OSSN.


Fourteen of the study patients opted for surgical deletion; in all cases an aggressive removal of the tumor, with wide and deep margins around the tumor land site, was followed by cryotherapy. The strong-growing approach was used because more conservative excisions had been associated with senior high OSSN recurrence rates in other patients. This is the low gear report on results of this fast-growing approach.


Eight study patients received coincidental reconstruction of the visual surface victimization amniotic membrane. Fifteen