The article from the National Birth Defects Prevention Study (NBDPS), "Diabetes Mellitus and Birth Defects," shows that significant women with pre-gestational diabetes mellitus (pre-pregnancy diagnosis of diabetes, such as type 1 or type 2 diabetes) are more likely than a mother with no diabetes or a mother with gestational diabetes mellitus (pregnancy-induced diabetes) to have a child with various types of single or multiple birth defects. This includes heart defects, defects of the mastermind and spine, oral clefts, defects of the kidneys and gastrointestinal tract and limb deficiencies. This study is the first to show the broad ambit and severeness of birth defects associated with type 1 and type 2 diabetes.
"The continued association of diabetes with a number of birth defects highlights the importance of increasing the number of women wHO receive the best possible preconception care, especially for those women diagnosed with diabetes," says Adolfo Correa, M.D., M.P.H., Ph.D., lead author and epidemiologist at CDC's National Center on Birth Defects and Developmental Disabilities. "Early and effective management of diabetes for pregnant women is critical in serving to non only forbid birth defects, but also to tighten the risk for former health complications for them and their children."
Researchers also ground that some of the pregnant women with gestational diabetes were more likely to throw a nipper with birth defects. Because birth defects associated with diabetes ar more likely to occur during the first trimester of gestation and before a diagnosis of gestational diabetes is made, the observed associations suggest that some of the mothers with it probably had undiagnosed diabetes before they became fraught. However symptoms went unnoticed until gestation.
Further, the associations of gestational diabetes with various birth defects were notable primarily among women world Health Organization had pre-pregnancy obesity, which is a known peril factor for both diabetes and birth defects. Preconception care also should be considered and promoted for women with pre-pregnancy fleshiness to foreclose birth defects and reduce the risk for health complications.
The NBDPS is a population-based, case-control cogitation that incorporates data from nine birth defect centers in the United States-Arkansas, California, Georgia, Iowa, Massachusetts, New York, North Carolina, Texas and Utah. These centers sustain been working on the largest study of birth defects causes ever undertaken in the United States. Researchers have gathered selective information from more than 30,000 participants and ar using this information to look at key questions on potential causes of birth defects.
Birth defects affect one in 33 infants and are a leading cause of infant mortality. For some parturition defects, some risk factors or causes have been identified; however, for the majority of birth defects the causes remain strange.
In the United States, the prevalence of gestational diabetes has been increasing in recent years and currently affects about septenary percent of all pregnancies, resulting in more than 200,000 cases per year. While it is unremarkably resolved shortly after delivery, women world Health Organization have had gestational diabetes are at increased risk of development type 2 diabetes in the future.
For more than information about birth defects, please visit here. For more data on diabetes, please visit http://www.cdc.gov/diabetes/, or call toll-free 1-800-CDC-INFO.
Centers for Disease Control and Prevention
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